2-Phenyl and 2-heterocyclic-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridines as inhibitors of TGF-β1 and activin A signalling-Reference-Cited by-同舟云学术

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2-Phenyl and 2-heterocyclic-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridines as inhibitors of TGF-β1 and activin A signalling

Published:2011-09 Issue:18 Volume:21 Page:5642-5645
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Ciayadi Rudy,Potdar Mahesh,Walton Kelly L.,Harrison Craig A.,Kelso Geoffrey F.,Harris Simon J.,Hearn Milton T.W.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference42 articles.

1. Regulation of Cell Proliferation, Apoptosis, and Carcinogenesis by Activin

2. Mechanisms of TGF-β-mediated apoptosis

3. Purification and properties of a type .beta. transforming growth factor from bovine kidney

4. Inhibition of vascular endothelial cell growth by activin-A.

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1. Advances in the discovery of activin receptor-like kinase 5 (ALK5) inhibitors;Bioorganic Chemistry;2024-06

2. Recent development of imidazole derivatives as potential anticancer agents;Physical Sciences Reviews;2022-01-13

3. Structure-Based Virtual Screening, Molecular Dynamics and Binding Free Energy Calculations of Hit Candidates as ALK-5 Inhibitors;Molecules;2020-01-09

4. Cascade and multicomponent synthesis of structurally diverse 2-(pyrazol-3-yl)pyridines and polysubstituted pyrazoles;Organic & Biomolecular Chemistry;2020

5. Inhibition of activin A signalling in a mouse model of pre-eclampsia;Placenta;2015-08

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