Cascade and multicomponent synthesis of structurally diverse 2-(pyrazol-3-yl)pyridines and polysubstituted pyrazoles

Author:

Barroso Raquel1234,Cabal María-Paz1234ORCID,Jiménez Azucena1234ORCID,Valdés Carlos1234ORCID

Affiliation:

1. Departamento de Química Orgánica e Inorgánica and Instituto Universitario de Química Organometálica “Enrique Moles”

2. Universidad de Oviedo

3. Oviedo 33006

4. Spain

Abstract

A wide diversity of polyheterocyclic systems including polysubstituted pyrazoles and pyridopyrazole polydentate ligands are readily assembled through cascade multicomponent processes from terminal alkynes and N-tosylhydrazones.

Funder

Ministerio de Economía y Competitividad

Fundación para el Fomento en Asturias de la Investigación Científica Aplicada y la Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference50 articles.

1. J. Elguero , A. M. S.Silva and A. C.Tomé , in Modern Heterocyclic Chemistry , ed. J. Alvarez-Builla , J. J. Vaquero and J. Barluenga , Wiley-VCH , Weinheim , vol. 2 , 2011 , pp. 635–725

2. From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles

3. Recent advances in bioactive pyrazoles

4. Recently reported biological activities of pyrazole compounds

5. Review: biologically active pyrazole derivatives

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