Pyridinyl aminohydantoins as small molecule BACE1 inhibitors-Reference-Cited by-同舟云学术

Pyridinyl aminohydantoins as small molecule BACE1 inhibitors

Published:2010-04 Issue:7 Volume:20 Page:2326-2329
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Zhou Ping,Li Yanfang,Fan Yi,Wang Zheng,Chopra Rajiv,Olland Andrea,Hu Yun,Magolda Ronald L.,Pangalos Menelas,Reinhart Peter H.,Turner M. James,Bard Jonathan,Malamas Michael S.,Robichaud Albert J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference16 articles.

1. Human β-Secretase (BACE) and BACE Inhibitors

2. Purification and cloning of amyloid precursor protein β-secretase from human brain

3. BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

4. Acylguanidines as Small-Molecule β-Secretase Inhibitors

5. Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency

Cited by 33 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Pyridine derivatives as anti-Alzheimer agents;Recent Developments in the Synthesis and Applications of Pyridines;2023

2. Synthetic strategies of functionalized pyridines and their therapeutic potential as multifunctional anti-Alzheimer's agents;Recent Developments in the Synthesis and Applications of Pyridines;2023

3. Computational screening of promising beta-secretase 1 inhibitors through multi-step molecular docking and molecular dynamics simulations - Pharmacoinformatics approach;Journal of Molecular Structure;2020-04

4. Nature of the Nucleophilic Oxygenation Reagent Is Key to Acid-Free Gold-Catalyzed Conversion of Terminal and Internal Alkynes to 1,2-Dicarbonyls;The Journal of Organic Chemistry;2019-12-18

5. Fluoro-benzimidazole derivatives to cure Alzheimer’s disease: In-silico studies, synthesis, structure-activity relationship and in vivo evaluation for β secretase enzyme inhibition;Bioorganic Chemistry;2019-07