Acylguanidines as Small-Molecule β-Secretase Inhibitors-Reference-Cited by-同舟云学术

Acylguanidines as Small-Molecule β-Secretase Inhibitors

Published:2006-09-15 Issue:21 Volume:49 Page:6158-6161
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cole Derek C.¹,Manas Eric S.¹,Stock Joseph R.¹,Condon Jeffrey S.¹,Jennings Lee D.¹,Aulabaugh Ann¹,Chopra Rajiv¹,Cowling Rebecca¹,Ellingboe John W.¹,Fan Kristi Y.¹,Harrison Boyd L.¹,Hu Yun¹,Jacobsen Steve¹,Jin Guixan¹,Lin Laura¹,Lovering Frank E.¹,Malamas Michael S.¹,Stahl Mark L.¹,Strand James¹,Sukhdeo Mohani N.¹,Svenson Kristine¹,Turner M. James¹,Wagner Erik¹,Wu Junjun¹,Zhou Ping¹,Bard Jonathan¹

Affiliation:

1. Chemical and Screening Sciences, Wyeth Research, 401 N. Middletown Road, Pearl River, New York 10965, Chemical and Screening Sciences, Wyeth Research, 200 Cambridge Park Drive, Cambridge, Masssachusetts 02139, Chemical and Screening Sciences, Wyeth Research, Princeton, New Jersey 08852, Discovery Neuroscience, Wyeth Research, Princeton, New Jersey 08852, and Chemical and Screening Sciences, Wyeth Research, 500 Arcola Road, Collegeville, Pennsylvania 19426

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0607451

Reference27 articles.

1. Translating cell biology into therapeutic advances in Alzheimer's disease

2. Cellular mechanisms of beta -amyloid production and secretion

3. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity

4. α-Haemolysin of uropathogenic E. coli induces Ca2+ oscillations in renal epithelial cells

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