Synthesis of 7-benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine and its analogs as bombesin receptor subtype-3 agonists-Reference-Cited by-同舟云学术

Synthesis of 7-benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine and its analogs as bombesin receptor subtype-3 agonists

Published:2010-05 Issue:9 Volume:20 Page:2785-2789
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Guo Cheng,Guzzo Peter R.,Hadden Mark,Sargent Bruce J.,Yet Larry,Kan Yanqing,Palyha Oksana,Kelly Theresa M.,Guan Xiaoming,Rosko Kim,Gagen Karen,Metzger Joseph M.,Dragovic Jasminka,Lyons Kathryn,Lin Linus S.,Nargund Ravi P.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference13 articles.

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2. Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonists

3. Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity

4. Hadden, M.; Goodman, A.; Guo, C.; Guzzo, P. R.; Henderson, A. J.; Pattamana, K.; Ruenz, M.; Sargent, B. J.; Swenson, B.; Yet, L.; Liu, J.; He, S.; Sebhat, I. K.; Lin, L. S.; Tamvakopoulos, C.; Peng, Q.; Kan, Y.; Palyha, O.; Kelly, T. M.; Guan, X.; Reitman, M. L.; Nargund, R. P. Bioorg. Med. Chem. Lett. 2010, 20, in press.

5. Inhibitors of gastric acid secretion: antisecretory 2-pyridylurea derivatives

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