3-[3-Fluoro-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)phenyl]-4-methylpyridine: a highly potent and orally bioavailable metabotropic glutamate subtype 5 (mGlu5) receptor antagonist-Reference-Cited by-同舟云学术

3-[3-Fluoro-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)phenyl]-4-methylpyridine: a highly potent and orally bioavailable metabotropic glutamate subtype 5 (mGlu5) receptor antagonist

Published:2004-11 Issue:22 Volume:14 Page:5477-5480
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Poon Steve F.,Eastman Brian W.,Chapman Deborah F.,Chung Janice,Cramer Merryl,Holtz Gregory,Cosford Nicholas D.P.,Smith Nicholas D.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. Glutamate receptors in the mammalian central nervous system

2. The Metabotropic Glutamate Receptors: Structure, Activation Mechanism and Pharmacology

3. PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS

4. Ligands for Glutamate Receptors: Design and Therapeutic Prospects

5. Metabotropic Glutamate Receptor Involvement in Models of Acute and Persistent Pain: Prospects for the Development of Novel Analgesics

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Aryl Diazonium Salt‐Triggered Cyclization and Cycloaddition Reactions: Past, Present, and Future;Chinese Journal of Chemistry;2020-07-08

2. Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures;Journal of Medicinal Chemistry;2018-02-18

3. Past, Present and Future of Antiepileptic Drug Therapy - Finding a Place for Heterocyclics;Mini-Reviews in Medicinal Chemistry;2015-07-31

4. Cognitive Enhancers (Nootropics). Part 1: Drugs interacting with Receptors. Update 2014;Journal of Alzheimer's Disease;2014-07-25

5. Cognitive Enhancers (Nootropics). Part 1: Drugs Interacting with Receptors;Journal of Alzheimer's Disease;2012-11-14