Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes-Reference-Cited by-同舟云学术

Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes

Published:2012-06 Issue:12 Volume:22 Page:3873-3878
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

McCoull William,Addie Matthew S.,Birch Alan M.,Birtles Susan,Buckett Linda K.,Butlin Roger J.,Bowker Suzanne S.,Boyd Scott,Chapman Stephen,Davies Robert D.M.,Donald Craig S.,Green Clive P.,Jenner Chloe,Kemmitt Paul D.,Leach Andrew G.,Moody Graeme C.,Morentin Gutierrez Pablo,Newcombe Nicholas J.,Nowak Thorsten,Packer Martin J.,Plowright Alleyn T.,Revill John,Schofield Paul,Sheldon Chris,Stokes Steve,Turnbull Andrew V.,Wang Steven J.Y.,Whalley David P.,Matthew Wood J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. Diacylglycerol acyltransferases: Potential roles as pharmacological targets

2. Antisense and small-molecule modulation of diacylglycerol acyltransferase

3. Inhibition of Triglyceride Synthesis as a Treatment Strategy for Obesity

4. Discovery of a Potent, Selective, and Orally Efficacious Pyrimidinooxazinyl Bicyclooctaneacetic Acid Diacylglycerol Acyltransferase-1 Inhibitor

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