Discovery of novel hedgehog antagonists from cell-based screening: Isosteric modification of p38 bisamides as potent inhibitors of SMO-Reference-Cited by-同舟云学术

Discovery of novel hedgehog antagonists from cell-based screening: Isosteric modification of p38 bisamides as potent inhibitors of SMO

Published:2012-07 Issue:14 Volume:22 Page:4907-4911
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Yang Bin,Hird Alexander W.,Russell Daniel John,Fauber Benjamin P.,Dakin Les A.,Zheng Xiaolan,Su Qibin,Godin Robert,Brassil Patrick,Devereaux Erik,Janetka James W.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference30 articles.

1. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

2. Transducing the Hedgehog Signal

3. Vertebrate Smoothened functions at the primary cilium

4. Cilia and Developmental Signaling

5. Vertebrate Smoothened functions at the primary cilium

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