Critical role of a methyl group on the γ-lactone ring of annonaceous acetogenins in the potent inhibition of mitochondrial complex I-Reference-Cited by-同舟云学术

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Critical role of a methyl group on the γ-lactone ring of annonaceous acetogenins in the potent inhibition of mitochondrial complex I

Published:2013-03 Issue:5 Volume:23 Page:1217-1219
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Kojima Naoto,Abe Masato,Suga Yuki,Ohtsuki Kazufumi,Tanaka Tetsuaki,Iwasaki Hiroki,Yamashita Masayuki,Miyoshi Hideto

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference44 articles.

1. Recent advances in annonaceous acetogenins

2. Annonaceous Acetogenins: Recent Progress

3. Acetogenins from Annonaceae: recent progress in isolation, synthesis and mechanisms of action

4. The mitochondrial complex i inhibitor annonacin is toxic to mesencephalic dopaminergic neurons by impairment of energy metabolism

5. Annonacin, a Natural Mitochondrial Complex I Inhibitor, Causes Tau Pathology in Cultured Neurons

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1. A Review on Annona muricata and Its Anticancer Activity;Cancers;2022-09-19

2. Structure–antitumor activity relationship of hybrid acetogenins focusing on connecting groups between heterocycles and the linker moiety;RSC Advances;2022

3. Structure–Activity Relationships of Thiophene Carboxamide Annonaceous Acetogenin Analogs: Shortening the Alkyl Chain in the Tail Part Significantly Affects Their Growth Inhibitory Activity against Human Cancer Cell Lines;Chemical and Pharmaceutical Bulletin;2021-10-01

4. A Decade of Muricatacin Synthesis and Beyond;European Journal of Organic Chemistry;2020-08-11

5. Syntheses of C2′-Fluorinated Analogs of Solamin;Chemical and Pharmaceutical Bulletin;2020-07-01

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