Synthesis of 5α-cholestan-6-one derivatives and their inhibitory activities of NO production in activated microglia: Discovery of a novel neuroinflammation inhibitor-Reference-Cited by-同舟云学术

Synthesis of 5α-cholestan-6-one derivatives and their inhibitory activities of NO production in activated microglia: Discovery of a novel neuroinflammation inhibitor

Published:2014-02 Issue:4 Volume:24 Page:1222-1227
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Yang Ya-Xi,Zheng Long-Tai,Shi Jing-Jing,Gao Bo,Chen Yan-Ke,Yang Hui-Chi,Chen Hong-Li,Li Yuan-Chao,Zhen Xue-Chu

Funder

National Science Foundation of China

National Basic Research Plan (973) of the Ministry of Science and Technology of China

from Jiangsu Science and Technology Commission

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference38 articles.

1. Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

2. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

3. Microglia: a sensor for pathological events in the CNS

4. Role of Microglia in Inflammation-Mediated Neurodegenerative Diseases: Mechanisms and Strategies for Therapeutic Intervention

5. The Impact of Microglia-Derived Cytokines upon Gliosis in the CNS

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