Strategies to lower the Pgp efflux liability in a series of potent indole azetidine MCHR1 antagonists-Reference-Cited by-同舟云学术

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Strategies to lower the Pgp efflux liability in a series of potent indole azetidine MCHR1 antagonists

Published:2011-09 Issue:18 Volume:21 Page:5310-5314
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Lu Kai,Jiang Yu,Chen Bin,Eldemenky Eman M.,Ma Gil,Packiarajan Mathivanan,Chandrasena Gamini,White Andrew D.,Jones Kenneth A.,Li Boshan,Hong Sang-Phyo

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference27 articles.

1. Characterization of melanin-concentrating hormone in chum salmon pituitaries

2. The melanin-concentrating hormone system of the rat brain: An immuno- and hybridization histochemical characterization

3. Identification and characterization of a melanin-concentrating hormone receptor

4. A role for melanin-concentrating hormone in the central regulation of feeding behaviour

5. SALMONID MELANIN-CONCENTRATING HORMONE INHIBITS CORTICOTROPHIN RELEASE

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Model of P-Glycoprotein Ligand Binding and Validation with Efflux Substrate Matched Pairs;Journal of Medicinal Chemistry;2024-03-28

2. Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease;Journal of Medicinal Chemistry;2023-10-20

3. Antituberculosis drugs: reducing efflux = increasing activity;Drug Discovery Today;2017-03

4. Synthesis of polyhydroxylated azetidine iminosugars and 3-hydroxy-N-methylazetidine-2-carboxylic acid from d-glucose;Tetrahedron;2015-08

5. Stereoselective synthesis of activated 2-arylazetidines via imino-aldol reaction;Organic & Biomolecular Chemistry;2015

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