Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties-Reference-Cited by-同舟云学术

Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties

Published:2007-04 Issue:8 Volume:17 Page:2299-2304
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Martin Matthew W.,Newcomb John,Nunes Joseph J.,Bemis Jean E.,McGowan David C.,White Ryan D.,Buchanan John L.,DiMauro Erin F.,Boucher Christina,Faust Theodore,Hsieh Faye,Huang Xin,Lee Josie H.,Schneider Stephen,Turci Susan M.,Zhu Xiaotian

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. Defective expression of p56lck in an infant with severe combined immunodeficiency.

2. Profound block in thymocyte development in mice lacking p56lck

3. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

4. Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck: Synthesis, SAR, and in Vivo Antiinflammatory Activity

Cited by 34 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Furo[3,2-b]pyridine: Chemical synthesis, transformations and biological applications;Journal of Saudi Chemical Society;2024-09

2. Discovery of furopyridine-based compounds as novel inhibitors of Janus kinase 2: In silico and in vitro studies;International Journal of Biological Macromolecules;2024-03

3. Building explainable graph neural network by sparse learning for the drug-protein binding prediction;2023-08-29

4. Integrated continuous‐flow/batch protocol for ortho‐selective alkynylation of (hetero)aryl tosylates;Bulletin of the Korean Chemical Society;2023-05-16

5. DOCKSTRING: Easy Molecular Docking Yields Better Benchmarks for Ligand Design;Journal of Chemical Information and Modeling;2022-07-18