Benzo[c][2,7]naphthyridines as inhibitors of PDK-1-Reference-Cited by-同舟云学术

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Benzo[c][2,7]naphthyridines as inhibitors of PDK-1

Published:2009-09 Issue:17 Volume:19 Page:5225-5228
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Kim Kyung-Hee,Wissner Allan,Floyd Middleton B.,Fraser Heidi L.,Wang Yanong D.,Dushin Russell G.,Hu Yongbo,Olland Andrea,Guo Bing,Arndt Kim

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference15 articles.

1. PDK1, the master regulator of AGC kinase signal transduction

2. 3'-phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling

3. The Akt Pathway: Molecular Targets for Anti-Cancer Drug Development

4. Structure, regulation and function of PKB/AKT—a major therapeutic target

5. The Biology and Clinical Relevance of the PTEN Tumor Suppressor Pathway

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1. Eaton's reagent is an alternative of PPA: Solvent free synthesis, molecular docking and ADME studies of new angular and linear carbazole based naphtho naphthyridines;Tetrahedron;2023-04

2. Synthesis, In Vitro Cytotoxicity, and DFT Studies of Novel 2‐Amino Substituted Benzonaphthyridines as PDK1 Inhibitors;ChemistrySelect;2022-03-30

3. Synthesis and Biological Activity of 2,7-Naphthyridine Derivatives: An Overview;Current Organic Chemistry;2021-11

4. Isolation and Synthesis of Veranamine, an Antidepressant Lead from the Marine Sponge Verongula rigida;Journal of Natural Products;2020-03-31

5. The chemical diversity and structure-based discovery of allosteric modulators for the PIF-pocket of protein kinase PDK1;Journal of Enzyme Inhibition and Medicinal Chemistry;2019-01-01

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