Identification of novel gankyrin binding scaffolds by high throughput virtual screening
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry
Reference24 articles.
1. Discovery of multiple interacting partners of gankyrin, a proteasomal chaperone and an oncoprotein—evidence for a common hot spot site at the interface and its functional relevance;Nanaware;Proteins Struct Funct Bioinforma,2014
2. Chaperone-mediated pathway of proteasome regulatory particle assembly;Roelofs;Nature,2009
3. Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas;Higashitsuji;Nat Med,2000
4. Gankyrin Is an Ankyrin-Repeat Oncoprotein That Interacts with CDK4 Kinase and the S6 ATPase of the 26 S Proteasome;Dawson;J Biol Chem,2002
5. Gankyrin drives malignant transformation of chronic liver damage-mediated fibrosis via the Rac1/JNK pathway;Zhao;Cell Death Dis,2015
Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Synthesis and Evaluation of 2,5-Substituted Pyrimidines as Small-Molecule Gankyrin Binders;Future Medicinal Chemistry;2024-01-11
2. Gankyrin inhibits ferroptosis through the p53/SLC7A11/GPX4 axis in triple-negative breast cancer cells;Scientific Reports;2023-12-08
3. Gankyrin inhibits ferroptosis through the P53/SLC7A11/GPX4 axis in Triple-negative breast cancer cells;2023-10-05
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