Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2-Reference-Cited by-同舟云学术

Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2

Published:2010-04 Issue:7 Volume:20 Page:2383-2388
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Corbett Jeffrey W.,Freeman-Cook Kevin D.,Elliott Richard,Vajdos Felix,Rajamohan Francis,Kohls Darcy,Marr Eric,Zhang Hailong,Tong Liang,Tu Meihua,Murdande Sharad,Doran Shawn D.,Houser Janet A.,Song Wei,Jones Christopher J.,Coffey Steven B.,Buzon Leanne,Minich Martha L.,Dirico Kenneth J.,Tapley Susan,Kirk McPherson R.,Sugarman Eliot,James Harwood H.,Esler William

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference10 articles.

1. Acetyl-coenzyme A carboxylases: Versatile targets for drug discovery

2. Inhibitors of Mammalian Acetyl-CoA Carboxylase

3. Acetyl Coenzyme A Carboxylase System of Escherichia coli

4. Isozyme-nonselective N-Substituted Bipiperidylcarboxamide Acetyl-CoA Carboxylase Inhibitors Reduce Tissue Malonyl-CoA Concentrations, Inhibit Fatty Acid Synthesis, and Increase Fatty Acid Oxidation in Cultured Cells and in Experimental Animals

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