Identification and optimisation of novel and selective small molecular weight kinase inhibitors of mTOR-Reference-Cited by-同舟云学术

Identification and optimisation of novel and selective small molecular weight kinase inhibitors of mTOR

Published:2009-10 Issue:20 Volume:19 Page:5898-5901
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Menear Keith A.,Gomez Sylvie,Malagu Karine,Bailey Christine,Blackburn Kristel,Cockcroft Xiao-Ling,Ewen Sally,Fundo Alexandra,Gall Armelle Le,Hermann Gesine,Sebastian Luisa,Sunose Mihiro,Presnot Thomas,Torode Eleanor,Hickson Ian,Martin Niall M.B.,Smith Graeme C.M.,Pike Kurt G.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

1. Targeting mTOR signaling for cancer therapy

2. Targeting the PI3K–AKT–mTOR pathway: progress, pitfalls, and promises

3. A mammalian protein targeted by G1-arresting rapamycin–receptor complex

4. RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

5. Phosphatidylinositol 3-kinase related kinases

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