From Synergy to Monotherapy: Discovery of Novel 2,4,6-Trisubstituted Triazine Hydrazone Derivatives with Potent Antifungal Potency <i>In Vitro</i> and <i>In Vivo</i>-Reference-Cited by-同舟云学术

From Synergy to Monotherapy: Discovery of Novel 2,4,6-Trisubstituted Triazine Hydrazone Derivatives with Potent Antifungal Potency In Vitro and In Vivo

Published:2024-02-21 Issue:5 Volume:67 Page:4007-4025
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Xie Fei¹^ORCID,Hao Yumeng¹,Liu Yu¹,Bao Junhe¹,Wang Ruina¹,Chi Xiaochen²,Wang Ting¹,Yu Shichong¹,Jin Yongsheng¹,Li Liping³,Jiang Yuanying³,Zhang Dazhi¹³,Yan Lan¹,Ni Tingjunhong³^ORCID

Affiliation:

1. School of Pharmacy, The Center for Basic Research and Innovation of Medicine and Pharmacy (MOE), Naval Medical University, No.325 Guohe Road, Shanghai 200433, China

2. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenyang 110016, China

3. Department of Pharmacy, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, No.1239 Siping Road, Shanghai 200072, China

Funder

Second Military Medical University

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02292

Reference44 articles.

1. Worldwide emergence of resistance to antifungal drugs challenges human health and food security

2. COVID-19-associated fungal infections

3. How to bolster the antifungal pipeline

4. Hidden Killers: Human Fungal Infections

5. The Changing Epidemiology of Invasive Fungal Infections

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