Novel 2-methoxyacylhydrazones as potent, selective PDE10A inhibitors with activity in animal models of schizophrenia-Reference-Cited by-同舟云学术

Novel 2-methoxyacylhydrazones as potent, selective PDE10A inhibitors with activity in animal models of schizophrenia

Published:2012-09 Issue:17 Volume:22 Page:5595-5599
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Cutshall Neil S.,Onrust Rene,Rohde Alex,Gragerov Sasha,Hamilton Lauren,Harbol Kevin,Shen Hui-Rong,McKee Shawn,Zuta Charles,Gragerova Galina,Florio Vince,Wheeler Thomas N.,Gage Jennifer L.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Emerging Opportunities for Antipsychotic Drug Discovery in the Postgenomic Era

2. Preclinical Characterization of Selective Phosphodiesterase 10A Inhibitors: A New Therapeutic Approach to the Treatment of Schizophrenia

3. Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases

4. PDE10A Inhibitors: Novel Therapeutic Drugs for Schizophrenia

5. DeMartinis, N.; Banerjee, A.; Kumar, V.; Boyer, S.; Schmidt, C.; Arroyo, S. 3rd Biennial Schizophrenia International Research Society Conference, April 2012, poster.

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