Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases

Author:

Card Graeme L.,England Bruce P.,Suzuki Yoshihisa,Fong Daniel,Powell Ben,Lee Byunghun,Luu Catherine,Tabrizizad Maryam,Gillette Sam,Ibrahim Prabha N.,Artis Dean R.,Bollag Gideon,Milburn Michael V.,Kim Sung-Hou,Schlessinger Joseph,Zhang Kam Y.J.

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference52 articles.

1. Activation and selective inhibition of a cyclic AMP-specific phosphodiesterase, PDE-4D3;Alvarez;Mol. Pharmacol,1995

2. Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes;Ballard;J. Urol,1998

3. SB 207499 (Ariflo), a potent and selective second-generation phosphodiesterase 4 inhibitor;Barnette;J. Pharmacol. Exp. Ther,1998

4. Cyclic nucleotide phosphodiesterases;Beavo;Physiol. Rev,1995

5. Cyclic nucleotide research–still expanding after half a century;Beavo;Nat. Rev. Mol. Cell Biol,2002

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