Novel nucleotide triphosphates as potent P2Y2 agonists with enhanced stability over UTP-Reference-Cited by-同舟云学术

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Novel nucleotide triphosphates as potent P2Y2 agonists with enhanced stability over UTP

Published:2007-01 Issue:2 Volume:17 Page:558-561
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Davenport Richard J.,Diaz Paloma,Galvin Frances C.A.,Lloyd Steve,Mack Stephen R.,Owens Ray,Sabin Verity,Wynn Joanne

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference13 articles.

1. Therapeutic applications of ATP-(P2)-receptors agonists and antagonists

2. P2Y2 receptors agonists: Structure, activity and therapeutic utility

3. Synthesis and P2Y receptor activity of a series of uridine dinucleoside 5′-polyphosphates

4. Structure–activity relationships of dinucleotides: Potent and selective agonists of P2Y receptors

5. Pharmacology of INS37217 [P1-(Uridine 5′)-P4- (2′-deoxycytidine 5′)tetraphosphate, Tetrasodium Salt], a Next-Generation P2Y2 Receptor Agonist for the Treatment of Cystic Fibrosis

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1. Catalyst‐Free Intermolecular Sulfonyl/Fluoromethyl Heteroarylation of Vinyl Ethers via Visible‐Light‐Induced Charge Transfer;Chemistry – A European Journal;2022-02-23

2. Tools and drugs for uracil nucleotide-activated P2Y receptors;Pharmacology & Therapeutics;2018-10

3. Synthesis of substituted 2-(β-d-glucopyranosyl)-benzimidazoles and their evaluation as inhibitors of glycogen phosphorylase;Carbohydrate Research;2013-11

4. Synthesis of β-D-ribofuranosylbenzazoles using nitrile oxide addition chemistry;Arkivoc;2012-09-28

5. Pyrimidine Nucleotides with 4-Alkyloxyimino and Terminal Tetraphosphate δ-Ester Modifications as Selective Agonists of the P2Y4 Receptor;Journal of Medicinal Chemistry;2011-05-20

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