In vitro biotransformations of the prostaglandin D2 (DP) antagonist MK-0524 and synthesis of metabolites-Reference-Cited by-同舟云学术

In vitro biotransformations of the prostaglandin D2 (DP) antagonist MK-0524 and synthesis of metabolites

Published:2007-01 Issue:2 Volume:17 Page:301-304
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Nicoll-Griffith Deborah A.,Seto Carmai,Aubin Yves,Lévesque Jean François,Chauret Nathalie,Day Stephen,Silva José M.,Trimble Laird A.,Truchon Jean-François,Berthelette Carl,Lachance Nicolas,Wang Zhaoyin,Sturino Claudio,Braun Matt,Zamboni Robert,Young Robert N.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. Prostaglandin D 2 as a Mediator of Allergic Asthma

2. Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans

3. Sturino, C. F.; Lachance, N.; Boyd, M.; Berthelette, C.; Labelle, M., et al. J. Med. Chem., in press.

4. Drug−Protein Adducts: An Industry Perspective on Minimizing the Potential for Drug Bioactivation in Drug Discovery and Development

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