Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus-Reference-Cited by-同舟云学术

Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus

Published:2010-08 Issue:16 Volume:20 Page:4850-4854
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

McGuigan Christopher,Madela Karolina,Aljarah Mohamed,Gilles Arnaud,Brancale Andrea,Zonta Nicola,Chamberlain Stanley,Vernachio John,Hutchins Jeff,Hall Andrea,Ames Brenda,Gorovits Elena,Ganguly Babita,Kolykhalov Alexander,Wang Jin,Muhammad Jerry,Patti Joseph M.,Henson Geoffrey

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference14 articles.

1. An overview about hepatitis C: A devastating virus

2. Peginterferon and Ribavirin for Chronic Hepatitis C

3. Emerging drugs for hepatitis C

4. Structure−Activity Relationship of Heterobase-Modified 2‘-C-Methyl Ribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication

5. Structure−Activity Relationship of Purine Ribonucleosides for Inhibition of Hepatitis C Virus RNA-Dependent RNA Polymerase

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