Discovery of a potent and selective cell division cycle 7 inhibitor from 6-(3-fluoropyridin-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one derivatives as an orally active antitumor agent
Author:
Publisher
Elsevier BV
Subject
General Pharmacology, Toxicology and Pharmaceutics
Reference4 articles.
1. Identification of novel Cdc7 kinase inhibitors as anti-cancer agents that target the interaction with Dbf4 by the fragment complementation and drug repositioning approach;Cheng;EBioMedicine,2018
2. A CDC7 inhibitor sensitizes DNA-damaging chemotherapies by suppressing homologous recombination repair to delay DNA damage recovery;Iwai;Sci Adv,2021
3. MiR-200a with CDC7 as a direct target declines cell viability and promotes cell apoptosis in Wilm's tumor via Wnt/beta-catenin signaling pathway;Liang;Mol Cell Biochem,2021
4. CDC7 as a novel biomarker and druggable target in cancer;Liu;Clin Transl Oncol,2022
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