Inhibition of ALDH3A1-catalyzed oxidation by chlorpropamide analogues

Author:

Sládek Norman E.,Rekha Ganaganur K.,Lee Melinda J.C.,Nagasawa Herbert T.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference17 articles.

1. Aldehyde dehydrogenases and their role in carcinogenesis;Lindahl;Crit. Rev. Biochem. Mol. Biol.,1992

2. A.J. Townsend, K.D. Bunting, R.L. Haynes, L. Szweda, Protection by stably transfected hALDH3 against protein modification, toxicity, and apoptosis induced by aldehydes known to be generated by lipid peroxidation, Chem.-Biol. Int. (2001) (in press).

3. Constitutive and overexpressed human cytosolic class-3 aldehyde dehydrogenases in normal and neoplastic cells/secretions;Sládek;Adv. Exp. Med. Biol.,1995

4. Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines;Sládek;Curr. Pharm. Des.,1999

5. Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by the naturally occurring compound gossypol;Rekha;Adv. Exp. Med. Biol.,1997

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