Modulation by plant flavonoids and related phenolics of microsome catalyzed adduct formation between benzo[a]Pyrene and DNA

Author:

Shah G.M.,Bhattacharya R.K.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference52 articles.

1. Enzymatic conversion of benzo (a) pyrene leading predominantly to the diolepoxide r-7t-8-dihydroxy-t-910-oxy-78910-tetrahydrobenzo (a) pyrene through a single enantiomer of r-7t-8-dihydroxy-78-dihydrobenzo (a) pyrene;Yang,1976

2. Metabolic activation of benzo (a) pyrene proceeds by a diol-epoxide;Sims;Nature,1974

3. Benzo (a) pyrene-diolepoxides: mechanism of enzymatic formation and optically active intermediates;Yang;Science,1977

4. On the nature of the product which results when 78-dihydrodiolbenzo (a) pyrene is metabolized in vitro and bound to DNA;King;Chem.-Biol. Interact.,1976

5. Molecular and cellular mechanisms of chemical carcinogenesis;Weinstein,1980

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