Kinetics of DNA alkylation, depurination and hydrolysis of anti diol epoxide of benzo(a)pyrene and the effect of cadmium on DNA alkylation
Author:
Publisher
Elsevier BV
Subject
Toxicology,General Medicine
Reference46 articles.
1. Benzo[a]pyrene-nucleic acid derivative found in vivo: structure of a benzo[a]pyrenetetrahydrodiol epoxide-guanosine adduct
2. Comparison of pulmonary DNA adduct levels, measured by 32P-postlabelling and aryl hydrocarbon hydroxylase activity in lung parenchyma of smokers and ex-smokers
3. The reaction of trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene with DNA involves attack at the N7-position of guanine moieties
4. High ratio of alkali-sensitive lesions to total DNA modification induced by benzo(a)pyrene diol epoxide.
5. Polycyclic aromatic hydrocarbon-DNA adducts in lung tissue from lung cancer patients
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