The reaction of trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene with DNA involves attack at the N7-position of guanine moieties-Reference-Cited by-同舟云学术

The reaction of trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene with DNA involves attack at the N7-position of guanine moieties

Published:1978-01 Issue:1 Volume:20 Page:123-130
ISSN:0009-2797
Container-title:Chemico-Biological Interactions
language:en
Short-container-title:Chemico-Biological Interactions

Author:

Osborne M.R.,Harvey R.G.,Brookes P.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference26 articles.

1. Metabolic activation of benzo(a)pyrene proceeds by a diol epoxide;Sims;Nature (London),1974

2. Enzymatic conversion of benzo(a)pyrene leading predominantly to the diol epoxide r-7, t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene through a single enantiomer of r-7, t-8-dihydroxy-7,8-dihydrobenzo(a)pyrene;Yang,1976

3. Exceptional mutagenicity of a benzo(a)pyrene diol epoxide in cultured mammalian cells;Newbold;Nature,1976

4. Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cells;Huberman,1976

5. High mutagenicity and toxicity of a diol epoxide derived from benzo(a)pyrene;Wislocki;Biochem. Biophys. Res. Commun.,1976

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