Pyridine and piperidine derivatives as inhibitors of dihydrodipicolinic acid synthase, a key enzyme in the diaminopimelate pathway to l-lysine-Reference-Cited by-同舟云学术

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Pyridine and piperidine derivatives as inhibitors of dihydrodipicolinic acid synthase, a key enzyme in the diaminopimelate pathway to l-lysine

Published:1994-10 Issue:19 Volume:4 Page:2267-2272
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Couper Lynda,McKendrick John E.,Robins David J.,Chrystal Ewan J.T.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference15 articles.

1. The Pyruvate-Aspartic Semialdehyde Condensing Enzyme of Escherichia coli

2. Dihydrodipicolinic Acid Reductase

3. Purification and Characterization of Dihydrodipicolinate Synthase from Wheat Suspension Cultures

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1. A Nucleophilic Activity‐Based Probe Enables Profiling of PLP‐Dependent Enzymes;ChemBioChem;2023-03

2. Enhancing allosteric inhibition of dihydrodipicolinate synthase through the design and synthesis of novel dimeric compounds;RSC Medicinal Chemistry;2023

3. Synthesis and structure-activity relationship studies of 2,4-thiazolidinediones and analogous heterocycles as inhibitors of dihydrodipicolinate synthase;Bioorganic & Medicinal Chemistry;2021-12

4. Pursuing DHDPS: an enzyme of unrealised potential as a novel antibacterial target;MedChemComm;2019

5. Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues;Scientific Reports;2016-08-09

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