Acyl CoA:cholesterol acyltransferase (ACAT) inhibitors: ureas bearing heterocyclic groups bioisosteric for an imidazole-Reference-Cited by-同舟云学术

Acyl CoA:cholesterol acyltransferase (ACAT) inhibitors: ureas bearing heterocyclic groups bioisosteric for an imidazole

Published:1995-01 Issue:2 Volume:5 Page:167-172
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Wilde Richard G.,Billheimer Jeffrey T.,Germain Sandra J.,Gillies Peter J.,Higley C.Anne,Kezar Hollis S.,Maduskuie Thomas P.,Shimshick Edward S.,Wexler Ruth R.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Reduced cholesterol transmucosal transport in rats with inhibited mucosal acyl CoA:cholesterol acyltransferase and normal pancreatic function.

2. Inhibition of hepatic ACAT decreases ApoB secretion in miniature pigs fed a cholesterol-free diet.

3. Pharmacological Control of Hyperlipidoemia;Bell,1986

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