Application of lat gene disruption to increase the clavulanic acid production of Streptomyces clavuligerus
Author:
Publisher
Elsevier BV
Subject
Process Chemistry and Technology,Biochemistry,Bioengineering,Catalysis
Reference15 articles.
1. The Paralogous Pairs of Genes Involved in Clavulanic Acid and Clavam Metabolite Biosynthesis Are Differently Regulated in Streptomyces clavuligerus
2. Clavulanic acid, a β-lactamase inhibitor: biosynthesis and molecular genetics
3. Five Additional Genes Are Involved in Clavulanic Acid Biosynthesis in Streptomyces clavuligerus
4. The biosynthetic genes for clavulanic acid and cephamycin production occur as a âsuper-clusterâ in threeStreptomyces
5. A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: amplification results in overproduction of both beta-lactam compounds
Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Environmental Factors Modulate the Role of orf21 Sigma Factor in Clavulanic Acid Production in Streptomyces Clavuligerus ATCC27064;Bioengineering;2022-02-16
2. Flux balance analysis in the production of clavulanic acid byStreptomyces clavuligerus;Biotechnology Progress;2015-07-15
3. Mutation of the Streptomyces clavuligerus by traditional and molecular breeding to increase the biosynthesis of clavulanic acid;AFR J MICROBIOL RES;2012
4. attB site disruption in marine Actinomyces sp. M048 via DNA transformation of a site-specific integration vector;Biotechnology and Applied Biochemistry;2008-05-01
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