Computational investigation to identify potent inhibitors of the GTPase-Kirsten RAt sarcoma virus (K-Ras) mutants G12C and G12D
Author:
Funder
VIT University
Indian Council of Medical Research
Publisher
Elsevier BV
Subject
Health Informatics,Computer Science Applications
Reference81 articles.
1. A comprehensive survey of Ras mutations in cancer;Prior;Cancer Res.,2012
2. Somatic mutations affect key pathways in lung adenocarcinoma;Ding;Nature,2008
3. Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy;Santarpia;Expert Opin. Ther. Targets,2012
4. Ras history: the saga continues;Cox;Small GTPases,2010
5. Drugging the undruggable RAS: mission possible?;Cox;Nat. Rev. Drug Discov.,2014
Cited by 22 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Chlorogenic acid attenuates idiopathic pulmonary fibrosis: An integrated analysis of network pharmacology, molecular docking, and experimental validation;Biochemical and Biophysical Research Communications;2024-11
2. Unraveling the molecular basis for effective regulation of integrin α5β1 for enhanced therapeutic interventions;Biochemical and Biophysical Research Communications;2024-11
3. From farm to pharma: Investigation of the therapeutic potential of the dietary plants Apium graveolens L., Coriandrum sativum, and Mentha longifolia, as AhR modulators for Immunotherapy;Computers in Biology and Medicine;2024-10
4. A novel Imidazo[1,2-a]pyridine derivative modulates active KRASG12D through off-like conformational shifts in switch-I and switch-II regions, mimicking inactive KRASG12D;International Journal of Biological Macromolecules;2024-06
5. Novel spiroindoline derivatives targeting aldose reductase against diabetic complications: Bioactivity, cytotoxicity, and molecular modeling studies;Bioorganic Chemistry;2024-04
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3