CB-64D and CB-184: ligands with high σ2 receptor affinity and subtype selectivity

Author:

Bowen Wayne D.,Bertha Craig M.,Vilner Bertold J.,Rice Kenner C.

Publisher

Elsevier BV

Subject

Pharmacology

Reference12 articles.

1. A marked change of receptor affinity of the 2-methyl-5-(3-hydroxyphenyl)morphans upon attachment of an (E)-8-benzylidene moiety: synthesis and evaluation of a new class of σ receptor ligands;Bertha;J. Med. Chem.,1994

2. [3H]BIMU-1, a 5-hydroxytryptamine3 receptor ligand in NG-108 cells, selectively labels sigma-2 binding sites in guinea pig brain hippocampus;Bonhaus;J. Pharmacol. Exp. Ther.,1993

3. [3H](+)-Pentazocine: a potent and highly selective benzomorphan-based probe for sigma-1 receptors;Bowen;Mol. Neuropharmacol.,1993

4. Structure-activity relationships and evolution of sigma receptor ligands (1976-present);De Costa,1994

5. A new approach to the design of sigma-2 selective ligands: synthesis and evaluation of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethylamine-related polyamines at sigma-1 and sigma-2 receptor subtypes;De Costa;J. Med. Chem.,1994

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