Characterization of TNP-470-induced modifications to cell functions in HUVEC and cancer cells

Author:

Farinelle Sophie,Malonne Hugues,Chaboteaux Carole,Decaestecker Christine,Dedecker Robert,Gras Thierry,Darro Francis,Fontaine Jeanine,Atassi Ghanem,Kiss Robert

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference33 articles.

1. A fumagillin derivative angiogenesis inhibitor, AGM-1470, inhibits activation of cyclin-dependent kinases and phosphorylation of retinoblastoma gene product but not protein tyrosyl phosphorylation or protooncogene expression in vascular endothelial cells;Abe;Cancer Research,1994

2. Regression of metastatic liver tumors in rats treated with angiogenesis inhibitor TNP-470: occurrence of apoptosis and necrosis;Ahmed;Japanese Journal of Cancer Research,1997

3. In vitro and in vivo stimulation of the murine immune system by AGM-1470, a potent angiogenesis inhibitor;Antoine;American Journal of Pathology,1996

4. AGM-1470, a potent angiogenesis inhibitor, prevents the entry of normal but not transformed endothelial cells into the G1 phase of the cell cycle;Antoine;Cancer Research,1994

5. The microtubule-affecting drug paclitaxel has antiangiogenic activity;Belotti;Clinical Cancer Research,1996

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