Directed evolution of a penicillin V acylase from Bacillus sphaericus to improve its catalytic efficiency for 6-APA production
Author:
Funder
Major Science and Technology Program for Water Pollution Control and Treatment
Publisher
Elsevier BV
Subject
Applied Microbiology and Biotechnology,Biochemistry,Biotechnology,Bioengineering
Reference23 articles.
1. Penicillin acylase: enzyme production and its application in manufacture of 6-APA;Shewale;Process Biochem.,1989
2. Biotechnological advances on penicillin G acylase: pharmaceutical implications, unique expression mechanism and production strategies;Srirangan;Biotechnol. Adv.,2013
3. Penicillin V acylase: its potential in the production of 6-amonipenicillanic acid;Shewale;Enzyme Microb. Tech.,1997
4. Purification and characterization of YxeI, a penicillin acylase from Bacillus subtilis;Rathinaswamy;Int. J. Biol. Macromol.,2012
5. Newly discovered penicillin acylase activity of aculeacin A acylase from Actinoplanes utahensis;Torres-Bacete;Appl. Environ. Microbiol.,2007
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