Enhancing the biocatalytic synthesis of chiral drug intermediate by rational design an aldo-keto reductase from Bacillus megaterium YC4-R4
Author:
Publisher
Elsevier BV
Subject
Applied Microbiology and Biotechnology,Biochemistry,Biotechnology,Bioengineering
Reference29 articles.
1. Duloxetine;Knadler;Clin. Pharmacokinet.,2011
2. Biotransformations for the production of the chiral drug (S)-Duloxetine catalyzed by a novel isolate of Candida tropicalis;Soni;Appl. Microbiol. Biotechnol.,2005
3. Bioreductive production of enantiopure (S)-duloxetine intermediates catalyzed with ketoreductase ChKRED15;Ren;J. Mol. Catal. B-Enzym.,2015
4. A chemoenzymatic dynamic kinetic resolution approach to enantiomerically pure (R)- and (s)-duloxetine;Traff;J. Org. Chem.,2011
5. Biotransformations for the production of the chiral drug (S)-duloxetine catalyzed by a novel isolate of Candida tropicalis;Soni;Appl. Microbiol. Biotechnol.,2005
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Multi-strategy orthogonal enhancement and analysis of aldo-keto reductase thermal stability;International Journal of Biological Macromolecules;2024-04
2. Specific coenzyme preference switching for an aldo-keto reductase that synthesizes the chiral intermediate of duloxetine;Enzyme and Microbial Technology;2023-12
3. Mining of a novel reductase and its application for asymmetric reduction of p-methoxyacetophenone;Letters in Applied Microbiology;2023-08
4. Ketoreductase-assisted synthesis of chiral selective tert-butyl{5-[(4-cyanophenyl)(hydroxy)methyl]-2-fluorophenyl}carbamate: process minutiae, optimization and characterization;Chemical Papers;2023-02-06
5. Engineering ketoreductases for the enantioselective synthesis of chiral alcohols;Chemical Communications;2023
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3