Expression of human β- N -acetylhexosaminidase B in yeast eases the search for selective inhibitors

Author:

Krejzová Jana,Kulik Natallia,Slámová Kristýna,Křen Vladimír

Funder

Czech Science Foundation

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,Biochemistry,Biotechnology,Bioengineering

Reference38 articles.

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2. Direct determination of the substrate specificity of the α-active site in heterodimeric β-hexosaminidase A;Hou;Biochemistry,1996

3. Isolation of cDNA clones coding for the alpha-subunit of human beta-hexosaminidase. Extensive homology between the alpha- and beta-subunits and studies on Tay-Sachs disease;Korneluk;J. Biol. Chem.,1986

4. Gene encoding the human beta-hexosaminidase beta chain: extensive homology of intron placement in the alpha- and beta-chain genes;Proia;Proc. Natl. Acad. Sci. U. S. A.,1988

5. The X-ray crystal structure of human β-hexosaminidase B provides new insights into Sandhoff disease;Maier;J. Mol. Biol.,2003

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