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Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration

  • Published:2017-08 Issue: Volume:12 Page:8-17
  • ISSN:2213-2317
  • Container-title:Redox Biology
  • language:en
  • Short-container-title:Redox Biology

Author:

Hambright William Sealy,Fonseca Rene Solano,Chen Liuji,Na Ren,Ran Qitao

Funder

Department of Veteran Affairs

Alzheimer's Association

Publisher

Elsevier BV

Subject

Organic Chemistry,Biochemistry,Clinical Biochemistry

Reference31 articles.

1. A potential role for apoptosis in neurodegeneration and Alzheimer's disease;Cotman;Mol. Neurobiol.,1995

2. Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders;Mattson;Antioxid. Redox Signal.,2006

3. Inflammation in the early stages of neurodegenerative pathology;Khandelwal;J. Neuroimmunol.,2011

4. Oxidative stress and mitochondrial dysfunction in Alzheimer's disease;Wang;Biochim. Biophys. Acta,2013

5. Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial;Gordon;Lancet Neurol.,2007

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