The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading

Author:

Baulies Anna,Montero Joan,Matías Nuria,Insausti Naroa,Terrones Oihana,Basañez Gorka,Vallejo Carmen,Conde de La Rosa Laura,Martinez Laura,Robles David,Morales Albert,Abian Joaquin,Carrascal Montserrat,Machida Keigo,Kumar Dinesh B.U.,Tsukamoto Hidekazu,Kaplowitz Neil,Garcia-Ruiz Carmen,Fernández-Checa José C.

Funder

Plan Nacional de I+D

CIBEREHD

NIAAA/NIH

AGAUR of the Generalitat de Catalunya

CSIC

CSIC/UAB Proteomics Laboratory of IIBB-CSIC

ISCIII

FEDER

Publisher

Elsevier BV

Subject

Organic Chemistry,Biochemistry,Clinical Biochemistry

Reference51 articles.

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2. Role of lipid transfer proteins in the abnormal lipid content of Morris hepatoma mitochondria and microsomes;Crain;Cancer Res,1983

3. Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma;Montero;Cancer Res.,2008

4. Anticancer activity of the cholesterol exporter ABCA1 gene;Smith;Cell Rep.,2012

5. Cholesterol effects on BAX pore activation;Christenson;J. Mol. Biol.,2008

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