Synthesis and biological evaluation of purine-pyrazole hybrids incorporating thiazole, thiazolidinone or rhodanine moiety as 15-LOX inhibitors endowed with anticancer and antioxidant potential-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of purine-pyrazole hybrids incorporating thiazole, thiazolidinone or rhodanine moiety as 15-LOX inhibitors endowed with anticancer and antioxidant potential

Published:2019-06 Issue: Volume:87 Page:821-837
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Afifi Ola S.,Shaaban Omaima G.,Abd El Razik Heba A.,Shams El-Dine Shams El-Dine A.,Ashour Fawzia A.,El-Tombary Alaa A.,Abu-Serie Marwa M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference42 articles.

1. Synthesis of novel hybrids of pyrazole and coumarin as dual inhibitors of COX-2 and 5-LOX

2. Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse

3. The importance of 15-lipoxygenase inhibitors in cancer treatment

4. Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis

5. 15-Lipoxygenase inhibitors: a patent review

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