Design and synthesis of novel quinazolinone-pyrazole derivatives as potential α-glucosidase inhibitors: Structure-activity relationship, molecular modeling and kinetic study

Author:

Azimi Fateme,Azizian Homa,Najafi Mohammad,Hassanzadeh Farshid,Sadeghi-aliabadi Hojjat,Ghasemi Jahan B.,Ali Faramarzi Mohammad,Mojtabavi Somayeh,Larijani Bagher,Saghaei Lotfollah,Mahdavi Mohammad

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference80 articles.

1. Inhibition of glucose absorption in the rat jejunum: a novel action of alpha-D-glucosidase inhibitors;Hirsh;Gastroenterology,1997

2. Is there a role for α-glucosidase inhibitors in the prevention of type 2 diabetes mellitus?;Scheen;Drugs,2003

3. Alpha-glucosidase inhibitors in the early treatment of type 2 diabetes;van de Laar;Vasc. Health Risk Manage.,2008

4. Therapeutic potential of α-glucosidase inhibitors in type 2 diabetes mellitus: an evidence-based review;Joshi;Expert Opin. Pharmacother.,2015

5. The α-glucosidase I inhibitor castanospermine alters endothelial cell glycosylation, prevents angiogenesis, and inhibits tumor growth;Pili;Cancer Res.,1995

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