Novel thienopyrimidine analogues as potential metabotropic glutamate receptors inhibitors and anticancer activity: Synthesis, In-vitro, In-silico, and SAR approaches-Reference-Cited by-同舟云学术

Novel thienopyrimidine analogues as potential metabotropic glutamate receptors inhibitors and anticancer activity: Synthesis, In-vitro, In-silico, and SAR approaches

Published:2021-04 Issue: Volume:109 Page:104729
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Khedr Mohammed A.,Abu-Zied Khadiga M.,Zaghary Wafaa A.,Aly Ahmed S.,Shouman Dina N.,Haffez Hesham

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference98 articles.

1. M.J. Meegan, N.M. O’Boyle, Special Issue “Anticancer Drugs”, Multidisciplinary Digital Publishing Institute, 2019.

2. Evolution of cancer pharmacological treatments at the turn of the third millennium;Falzone;Front. Pharmacol.,2018

3. Combination therapy in combating cancer;Mokhtari;Oncotarget,2017

4. Glutamate receptor phosphorylation and trafficking in pain plasticity in spinal cord dorsal horn;Liu;Eur. J. Neurosci.,2010

5. AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis;Bonnet;Ann. Rheum. Dis.,2015

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