Design and synthesis of 4-anilinoquinazolines as Raf kinase inhibitors. Part 1. Selective B-Raf/B-RafV600E and potent EGFR/VEGFR2 inhibitory 4-(3-hydroxyanilino)-6-(1H-1,2,3-triazol-4-yl)quinazolines-Reference-Cited by-同舟云学术

Design and synthesis of 4-anilinoquinazolines as Raf kinase inhibitors. Part 1. Selective B-Raf/B-RafV600E and potent EGFR/VEGFR2 inhibitory 4-(3-hydroxyanilino)-6-(1H-1,2,3-triazol-4-yl)quinazolines

Published:2021-04 Issue: Volume:109 Page:104715
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Lee Cheng-I,Liao Chu-Bin,Chen Chih-Shang,Cheng Fen-Ying,Chung Yu-Hsuan,Wang Yu-Chuan,Ciou Sian-Yi,Hsueh Wen-Yun,Lo Tzu-Hao,Huang Guan-Ru,Huang Hsin-Yi,Tsai Chia-Shen,Lu Yu-Jung,Chuang Shih-Hsien,Huang Jiann-Jyh

Funder

Ministry of Science and Technology of the People's Republic of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference55 articles.

1. Oncogenic kinase signaling;Blume-Jensen;Nature,2001

2. Protein kinase biochemistry and drug discovery;Schwartz;Bioorg. Chem.,2011

3. Kinase-targeted cancer therapies: progress, challenges and future directions;Bhullar;Mol. Cancer,2018

4. Properties of FDA-approved small molecule protein kinase inhibitors;Roskoski;Pharmacol. Res.,2019

5. EGFR antagonists in cancer treatment;Ciardiello;N. Engl. J. Med.,2008

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