Structure-guided design of novel biphenyl-quinazoline derivatives as potent non-nucleoside reverse transcriptase inhibitors featuring improved anti-resistance, selectivity, and solubility-Reference-Cited by-同舟云学术

Structure-guided design of novel biphenyl-quinazoline derivatives as potent non-nucleoside reverse transcriptase inhibitors featuring improved anti-resistance, selectivity, and solubility

Published:2024-06 Issue: Volume:147 Page:107340
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Wang Jin-Si,Zhao Ke-Xin,Zhang Kun,Pannecouque Christophe,De Clercq Erik,Wang Shuai,Chen Fen-Er

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Reference32 articles.

1. Structure-Based Optimization of 2,4,5-Trisubstituted Pyrimidines as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Exploiting the Tolerant Regions of the Non-Nucleoside Reverse Transcriptase Inhibitors’ Binding Pocket;Zhao;J Med Chem,2023

2. Fluorine in Anti-HIV Drugs Approved by FDA from 1981 to 2023;Han;Eur J Med Chem,2023

3. Discovery of Novel Sulfonamide Substituted Indolylarylsulfones as Potent HIV-1 Inhibitors with Better Safety Profiles;Gao;Acta Pharm Sin B,2023

4. Insights into HIV-1 Reverse Transcriptase (RT) Inhibition and Drug Resistance from Thirty Years of Structural Studies;Singh;Viruses,2022

5. Recent Advances on Dual Inhibitors Targeting HIV Reverse Transcriptase Associated Polymerase and Ribonuclease H;Kang;Eur J Med Chem,2023

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1. Discovery of 2,4,6-trisubstituted pyrimidine derivatives as novel potent HIV-1 NNRTIs by exploiting the tolerant region II of the NNIBP;European Journal of Medicinal Chemistry;2024-11