1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inflammatory and analgesic agents with an improved gastric profile: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study

Author:

Sakr Asmaa,Kothayer Hend,Ibrahim Samy M.,Baraka Mohamed M.,Rezq Samar

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference52 articles.

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3. Discovery of novel nonsteroidal anti-inflammatory drugs and carbonic anhydrase inhibitors hybrids (NSAIDs − CAIs) for the management of rheumatoid arthritis;Akgul;J. Med. Chem.,2018

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5. Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase;Fletcher;J. Biol. Chem.,1992

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