Dihydrofolate reductase inhibition effect of 5-substituted pyrido[2,3-d]pyrimidines: Synthesis, antitumor activity and molecular modeling study-Reference-Cited by-同舟云学术

Dihydrofolate reductase inhibition effect of 5-substituted pyrido[2,3-d]pyrimidines: Synthesis, antitumor activity and molecular modeling study

Published:2019-09 Issue: Volume:90 Page:103076
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Abdelaziz Ola A.,El Husseiny Walaa M.,Selim Khalid B.,Eisa Hassan M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

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5. Inhibitors of dihydrofolate reductase as antitumor agents: design, synthesis and biological evaluation of a series of novel nonclassical 6-substituted pyrido [3, 2-d] pyrimidines with a three-to five-carbon bridge;Li;Bioorg. Med. Chem.,2018

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