Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase – The importance of accommodating the active site water-Reference-Cited by-同舟云学术

Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase – The importance of accommodating the active site water

Published:2014-12 Issue: Volume:57 Page:242-250
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Heyes Logan C.,Reichau Sebastian,Cross Penelope J.,Jameson Geoffrey B.,Parker Emily J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference39 articles.

1. The Shikimate Pathway — A Metabolic Tree with Many Branche

2. The Shikimate Pathway and Aromatic Amino Acid Biosynthesis in Plants

3. Potent Inhibitors of a Shikimate Pathway Enzyme from Mycobacterium tuberculosis

4. Synthesis and Biological Evaluation of New Nanomolar Competitive Inhibitors of Helicobacter pylori Type II Dehydroquinase. Structural Details of the Role of the Aromatic Moieties with Essential Residues

5. Experiences with the shikimate-pathway enzymes as targets for rational drug design

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