Design, synthesis and biological evaluation of new multi-target scutellarein hybrids for treatment of Alzheimer’s disease

Author:

Luo Keke,Chen Jiao,Li Hui,Wu Dirong,Du Yuanjiang,Zhao Shanshan,Liu Ting,Li Li,Dai Zeqin,Li Yongjun,Zhao Yonglong,Tang Lei,Fu Xiaozhong

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference66 articles.

1. Alzheimer's disease facts and figures;Alzheimer’s Association;Alzheimer’s Dement.,2021

2. P4–151: World Alzheimer report 2014: dementia and risk reduction;Wortmann;Alzheimer’s Dement.,2015

3. Novel anti-Alzheimer phenol-lipoyl hybrids: synthesis, physicochemical characterization, and biological evaluation;Pagoni;Eur. J. Med. Chem.,2020

4. New approaches to treating Alzheimer’s disease;Zheng;Perspect. Med. Chem.,2015

5. An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer's disease;Clark;Alzheimers Res. Ther.,2021

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