Simple pharmacokinetic models accounting for drug monitoring results of atomoxetine and its 4-hydroxylated metabolites in Japanese pediatric patients genotyped for cytochrome P450 2D6-Reference-Cited by-同舟云学术

Simple pharmacokinetic models accounting for drug monitoring results of atomoxetine and its 4-hydroxylated metabolites in Japanese pediatric patients genotyped for cytochrome P450 2D6

Published:2020-04 Issue:2 Volume:35 Page:191-200
ISSN:1347-4367
Container-title:Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Notsu Yuki,Shimizu Makiko,Sasaki Tatsuro,Nakano Ayane,Ota Miki,Yoshida Sayaka,Yamazaki Hiroshi

Publisher

Elsevier BV

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference24 articles.

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2. Physiologically based pharmacokinetic nodel of the CYP2D6 probe atomoxetine: extrapolation to special populations and drug-drug interactions;Huang;Drug Metab Dispos,2017

3. Physiologically based pharmacokinetic modelling of atomoxetine with regard to CYP2D6 genotypes;Kim;Sci Rep,2018

4. Identification of the human cytochromes P450 responsible for atomoxetine metabolism;Ring;Drug Metab Dispos,2002

5. Disposition and metabolic fate of atomoxetine hydrochloride: the role of CYP2D6 in human disposition and metabolism;Sauer;Drug Metab Dispos,2003

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1. Pharmacokinetic Models Scaled Up from Humanized Liver Mouse Data Can Account for Drug Monitoring Results of Atomoxetine and Its 4-Hydroxylated andN-Demethylated Metabolites in Pediatric Patients Genotyped for CytochromeP450 2D6;Drug Metabolism and Disposition;2023-10-25

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