Prediction of CNS occupancy of dopamine D2 receptor based on systemic exposure and in vitro experiments

Author:

Kanamitsu KayokoORCID,Arakawa Ryosuke,Sugiyama Yuichi,Suhara Tetsuya,Kusuhara Hiroyuki

Funder

New Energy and Industrial Technology Development Organization (NEDO), Japan

Japan Agency for Medical Research and development, AMED

JSPS KAKENHI

Publisher

Elsevier BV

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference36 articles.

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4. Positron emission tomography studies on D2 dopamine receptor occupancy and antipsychotic drug plasma levels in man;Nyberg;Int Clin Psychopharmacol,1995

5. Steady-state pharmacokinetics of a new antipsychotic agent perospirone and its active metabolite, and its relationship with prolactin response;Yasui-Furukori;Ther Drug Monit,2004

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