Synthesis of Leu-enkephalin peptidomimetics containing trifluoromethylalkenes as amide isopolar mimics

Author:

Eeda Venkateswararao,Selvaraju Manikandan,Altman Ryan A.

Funder

National Institutes of Health

National Institute on Drug Abuse

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Environmental Chemistry,Biochemistry

Reference36 articles.

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3. Dual inhibitors of enkephalin-degrading enzymes (neutral endopeptidase 24.11 and aminopeptidase N) as potential new medications in the management of pain and opioid addiction;Noble;NIDA Res Monogr.,1995

4. The design of metabolically-stable peptide analogs;Veber;Trends Neurosci.,1985

5. Methyl- and (trifluoromethyl)alkene peptide isosteres: synthesis and evaluation of their potential as β-turn promoters and peptide mimetics;Wipf;J. Org. Chem.,1998

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